H3F3A (Histone 3.3) G34W Immunohistochemistry

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H3F3A (Histone 3.3) G34W Immunohistochemistry

Giant cell tumor of bone (GCTB) is a locally aggressive subarticular tumor. Having recently reported that H3.3 G34W mutations are characteristic of this tumor type, we have now investigated the sensitivity and specificity of the anti-histone H3.3 G34W rabbit monoclonal antibody in a wide variety of tumors including histologic mimics of GCTB to assess its value as a diagnostic marker. We also de...

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ژورنال

عنوان ژورنال: American Journal of Surgical Pathology

سال: 2017

ISSN: 0147-5185

DOI: 10.1097/pas.0000000000000859